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MicroRNA miRNA is a class of
2020-04-06

MicroRNA (miRNA) is a class of highly conserved, non-coding small molecules containing 19–25 nucleotides. miRNAs are involved in the regulation of genes associated with cancer development and progression and therefore can act as oncogenes, by contributing to tumor formation,17, 18 or as tumor suppre
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br Methodology To simulate chip flow trajectory the
2020-04-06

Methodology To simulate chip flow trajectory, the force and torque acting on the chips in high pressure coolant are computed based on the control volume method [6]. During the setup, a typical gun drill chip and gun drill bit are imported into ANSYS CFX 14.0 and prescribed as stationary solids. T
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The mechanism by which these HIV PIs impair skeletal muscle
2020-04-06

The mechanism by which these HIV-PIs impair skeletal muscle palmitate transport and oxidation has been partially elucidated. CD36 (also referred to as fatty g-quadruplex translocase; FAT) is a transmembrane protein involved in the transport of long-chain fatty acids (LCFA) across cellular membranes
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In order to further evaluate cpt
2020-04-06

In order to further evaluate cpt1a function, we determined its tissue distribution in large yellow croaker. The mRNA levels of cpt1a were detected in all the tested tissues, but at varying levels. cpt1a mRNA expression was the highest in liver among different tissues, similar to reports in other fis
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Introduction Primitive neuroectodermal tumors PNETs are mali
2020-04-06

Introduction Primitive neuroectodermal tumors (PNETs) are malignant, small round cell tumors of neural crest origin which typically arises from bone or soft tissue in the trunk/axial skeleton/paraspinal regions in adolescents and young adults and comprises of 50% cases with local recurrence and met
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br Enzyme catalysis A biochemically spontaneous
2020-04-06

Enzyme catalysis A biochemically spontaneous process proceeds in a direction where free NS 11021 australia of the system decreases. However, every spontaneous or energetically favorable reaction needs to overcome an energy barrier known as the activation energy barrier because of the formation of
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Nitric oxide NO is synthesized by conversion of the l
2020-04-03

Nitric oxide (NO) is synthesized by conversion of the l-arginine to NO and l-citrulline through reaction which is catalyzed by nitric oxide synthetase (NOS) (Knowles and Moncada, 1994). NO as an important molecule not only play a role as second messenger but also binds to cytochrome c oxidase and de
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Bmp products such as Fig are persistent pollutants that
2020-04-03

Bmp7 products, such as 7–9 (Fig. 2), are persistent pollutants that accumulate in the marine environment and can potentially be transferred to the human population via our trophic connections to the oceans (Wan et al., 2009). In addition to potentially addressing the mechanistic curiosities describe
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Recently we have observed that
2020-04-03

Recently, we have observed that pharmacological PPARα and PPARβ/δ activation regulates the expression of genes involved in FA metabolism such as FAT/CD36, CPT1, LCAD and MCAD in Sertoli cells. We have also observed that PPARβ/δ activation can simultaneously regulate the expression of the above-menti
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Carnitine acetyltransferase CrAT transesterifies short chain
2020-04-03

Carnitine acetyltransferase (CrAT) transesterifies short-chain acyl-CoAs, and is located both in mitochondria and peroxisomes. In yeasts and mammals this protein is the product of a single gene [20,21] and the sorting to different organelles is evolutionary conserved, although the mechanism of diffe
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histamine receptor In previous works Wang et al the PR
2020-04-03

In previous works (Wang et al. [4,5]), the PR-CPA EoS has been applied to describe the solubilities of hydrocarbons (including methane, ethane, propane, n-butane, n-pentane, n-hexane, benzene, toluene, and ethyl-benzene) and mercaptans (including methyl mercaptan and ethyl mercaptan) in aqueous MDEA
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Introduction Taenia solium is the causative
2020-04-03

Introduction Taenia solium is the causative agent of human taeniasis/cysticercosis and porcine cysticercosis, a major health problem and a veterinary economic challenge in developing countries of Latin America, Africa, and Asia. In Mexico, approximately 500 human neurocysticercosis cases were repor
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A number of immune relevant genes have been
2020-04-03

A number of immune-relevant genes have been studied to explore the immunologic mechanisms in large yellow croakers; however, the chemokine receptor CXCR family has never been studied in this organism. Chemokines are a large superfamily of chemotactic cytokines that are utilized to direct the traffic
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Depending on the needs of the product to be
2020-04-03

Depending on the needs of the product to be preserved, there are several levels of barrier packaging. Usually they are classified into low and high barriers. High barriers have a low oxygen transmittal rate, low moisture vapor transmission rate, and a high tensile strength, or puncture resistance. W
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br Theory br Method To test
2020-04-03

Theory Method To test our hypotheses as shown in Fig. 1, we conducted a survey at an international media company (hereafter referred to as ‘MediaCo’) headquartered in the UK. Its 5500 employees are dispersed throughout the world, partly due to massive acquisitions within the past decade. In ex
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