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Although there is a growing interest in
2020-08-04

Although there is a growing interest in the biological production of xylitol from renewable materials (Albuquerque et al., 2014, Dhar et al., 2016), at present, most of the xylitol is produced on commercial scale by traditional chemical approach that include hydrogenation of pure d-xylose derived fr
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Vitamin D3 receptor br CRF involvement in fear anxiety
2020-08-03

CRF involvement in fear/anxiety Given the ability of CRF and CRF1+ Vitamin D3 receptor to regulate BLA and CeA neuronal activity, it is unsurprising that the CRF system has also been shown to regulate fear and anxiety-like behaviors. Acute stress enhances CRF release in the amygdala (Koob & Hein
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Data presented may also be relevant
2020-08-03

Data presented may also be relevant in the context of acute myeloid leukemia and myelodysplastic syndrome treatment by 5-AzaD (Decitabine) [46]. In fact, IL-18 has been implicated in the pathogenesis of both hematologic malignancies [47,48] which suggests reinforcement of IL-18BP as potential aspect
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Neuroinflammation is the one of the
2020-08-03

Neuroinflammation is the one of the emerging causal factors contributing to these cognitive deficits. Therefore, we further tested the hypothesis that neuroinflammation is a key component contributing to the progression of spatial memory deficits during HH. Spatial memory deficits were observed afte
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When multiple concurrent users simultaneously make a request
2020-08-03

When multiple concurrent users simultaneously make a request for GUI initialization, the server side is not able to respond to all users at the same time. Therefore, the “min” column in Fig. 17 gives the time taken for the first user to receive the response and complete the initialization process. T
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Vinpocetine In anaphase APC CCDC recruits substrates while t
2020-08-03

In anaphase, APC/CCDC20 recruits substrates, while the APC2–APC11 cullin–RING catalytic core engages, positions, and activates transient E2∼Ub intermediates (e.g., UBE2C∼Ub, where ‘∼’ refers to thioester bond) from which Ub is transferred to a coactivator-bound substrate (Figure 2B, Conformation VI)
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Large number of experimental data were used to develop
2020-08-03

Large number of experimental data were used to develop these correlations between mechanical strength and durability of the RHA added cement concrete. A least square method was employed to arrive the empirical constants and model parameters with higher accuracy. And the final models are given in the
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br Materials and Methods br Results br Discussion The abilit
2020-08-03

Materials and Methods Results Discussion The ability of pathogens to modulate the host fibrinolytic system is a crucial characteristic for tissue invasion. Plasminogen is an abundant protein of the host fibrinolytic system which upon activation into plasmin dissolves fibrin clots [12]. Eith
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br Genes encoding the DGAT enzymes br
2020-08-03

Genes encoding the DGAT enzymes Membrane topology and structure-function relationships The evolutionary divergence in the gene sequences of the DGAT enzymes is reflected in their predicted protein structures [73]. Through multiple sequence alignment of DGATs, including 59 DGAT1s from 48 organi
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The oxidation of the lipid fraction of meat is an
2020-08-01

The oxidation of the lipid fraction of meat is an extremely complex process because of the high sensitivity of oxidation products to decomposition, their reactions with other components, the complex effect of catalysts and the presence of antioxidants. These changes are the main cause of limited she
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Progesterone has long been known to be absolutely indispensa
2020-07-31

Progesterone has long been known to be absolutely indispensable for the establishment of the receptive endometrium, but is now being recognized as possibly also contributing immunologically to the sustenance of pregnancy by interacting with the maternal immune system. Almost 40 years ago Stites refe
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The covalent linkage of hemin with nucleic
2020-07-31

The covalent linkage of hemin with nucleic acids is one of the alternative strategies for catalytic capacity improvement of hemin, which has been proved to significantly improve hemin’s solubility and recover peroxidase activity [28]. In previous work, we have investigated the catalytic properties a
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The expression of ET ETAR proteins appears to
2020-07-31

The expression of ET-1/ETAR proteins appears to be different in various cancers. Wülfing et al [33] observed staining of ET-1 in 26.8% of ABT 724 trihydrochloride cancer tissue samples and in 58.8% in ETAR of the same cases. In another study, Eltze et al [34] identified ET-1 and ETAR staining in 62
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The consumption of a high fat and or high
2020-07-31

The consumption of a high-fat and/or high-fructose diet has been implicated in the progression of many diseases, including metabolic disorders, NAFLD, and NASH (Ouyang et al., 2008, Yang et al., 2012). In the present study, oxidative stress and liver injury were induced in the HFFD mice as demonstra
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MTX and MTXPGs block the activity of
2020-07-31

MTX and MTXPGs block the activity of the key enzyme DHFR (Fig. 1), which converts folates to their active forms – dihydrofolate (DHF) and tetrahydrofolate (THF). MTXPGs also potently inhibit thymidylate synthase (TS). Furthermore, during dTMP synthesis, TS utilizes the cofactor 5,10-methylene THF, w
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