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Here we report for the first
2021-04-01
Here, we report for the first time that EphB4 contains two NLS sequences and localises to the nucleus. This is mediated via an importin-α pathway and we show that EphB4 could potentially have a direct role in gene regulation. These data provide new insight into Eph receptor localisation and action a
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ACAT may act as a dimer of dimer Within
2021-04-01
ACAT1 may act as a dimer of dimer [38]. Within each dimer, it may contain two identical sterol substrate sites (designated as site S), and one or two sterol activator site(s) (designated as site A). Site S preferentially binds pregnenolone (PREG); it can also bind a variety of sterols that contain 3
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br Materials and methods br Results
2021-04-01
Materials and methods Results Discussion Enolase (2-phospho-D-glycerate hydrolase) is a glycolytic enzyme that is also involved with various important roles in the intracellular and extracellular space (Copley, 2003; S. Zhang et al., 2015) such as transcriptional regulation, apoptosis, grow
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br Results br Discussion Many studies have
2021-04-01
Results Discussion Many studies have shown that intrinsic properties of the E2 enzyme govern the nature of the Ub modification, including both the multiplicity of the Ub modification and the specific DL-TBOA type in the case of polyubiquitin chains [3], [4], [9], [14]. Whereas previous studies
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br Experimental Procedures br Author Contributions br Acknow
2021-04-01
Experimental Procedures Author Contributions Acknowledgments Research in the Davis laboratory was supported by grants 4R37NS019904, 5R01NS052351, and 1R35NS097224 from NINDS. Research in the Martemyanov laboratory was supported by grants DA036596 and DA026405 from NIDA, and MH105482 from NI
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br Materials and methods br Results br
2021-04-01
Materials and methods Results Discussion Tuberculosis is caused by the mycobacterium M. tuberculosis, a pathogen able to survive in the hostile conditions through sophisticated defence mechanisms. In an attempt to clarify some aspects of the M. tuberculosis defence mechanisms, we have inves
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In conclusion over expression of Stokesia epoxygenase SlEPX
2021-04-01
In conclusion, over-expression of Stokesia epoxygenase (SlEPX) in soybean seeds led to some unusual seed phenotypes. These effects can be overcome by coexpression of Vernonia DGATs (VgDGAT1 & 2). The DGATs can specifically transfer vernolic Rosiglitazone maleate into TAG, largely reducing vernolic
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Currently it is not known if drought induces changes
2021-03-31
Currently, it is not known if drought induces changes in the cysteine protease c-di-AMP of soybean nodules. The available annotation of the soybean genome, in Phytozome (www.phytozome.net) has identified 706 C1 cysteine protease sequences and 75 C13 cysteine proteases. We have previously reported e
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For the first time the
2021-03-31
For the first time, the V. carinata transcriptome was analyzed and its transcript coding sequences comprehensively characterized. The non-redundant contigs encoding putative CysPs were identified and their (-)-Bicuculline methobromide patterns in different tissues were investigated. Our study show t
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br Discussion Our data demonstrate that
2021-03-31
Discussion Our data demonstrate that the bicyclam AMD3100 strongly interacts with CXCR-4, whereas DS and AR177, two other compounds that also interfere with virus entry into the quality (and interfere with virus binding), do not. AMD3100 is a unique compound in that it interferes with the chemoki
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br Results with scrubbing process Based on the
2021-03-31
Results with scrubbing process Based on Dipraglurant discussion of Section 4.4 and area availability results of the previous section, scrubbing process, at the pixel processing rate, was included to mitigate error accumulation on the arrays and on the line-buffer. Eight sequential signals, plus t
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br Patients and methods br Results
2021-03-31
Patients and methods Results Table 1 shows relevant demographic and clinical characteristics of the 123 patients in the cohort. BAL fluid samples were obtained at a median of 172.5 days after allo-HSCT (range 3 days to five years). Discussion The definitive abandonment of traditional cultu
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br Conclusion br Introduction Biological wastewater treatmen
2021-03-31
Conclusion Introduction Biological wastewater treatment is targeted towards the removal of phosphorous, nitrogen and organic substances by the metabolic activity of a diverse activated sludge microbial community. More precisely, it is based on the versatile catalytic activity of the microbial
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br Activatable optical imaging probes Optical fluorescence i
2021-03-31
Activatable optical imaging probes Optical fluorescence imaging, which directly detects photons emitted from fluorescent probes, has become as a powerful analytical method to study biological processes both in vitro and in vivo. It is characterized by high sensitivity, is free of radioactive irra
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With this we find This is all that one can
2021-03-31
With this we find This is all that one can say for , however when there is also a negative bwx mg solution which is a bound state. One must have in this case, up to a normalization constantwith K>0. The delta potential now imposes or and one has as the energy of the bound state. The enzyme anal
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