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With this in mind we were dismayed that
2019-06-01
With this in mind, we were dismayed that the 133rd session of the WHO Executive Board last year failed to reach consensus on the adoption of a provisional agenda on improving the health and wellbeing of LGBT people. Young people have shown an aptitude for co-operation in improving LGBT health where
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br Case report We report
2019-06-01
Case report We report a case of an 18 year-old Caucasian male who was found to have thrombocytopenia at birth, with a platelet count of 58,000/mm3. Bone marrow biopsy was first performed in 1993, at 13 months of age, and showed 70–80% cellular marrow with occasional megakaryocytes and no evidence
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(±)-Nutlin-3 br A new model of
2019-06-01
A new model of human wellbeing is emerging to guide humanity in the Anthropocene. In essence, it recognises that wellbeing depends on enabling every person to lead a life of dignity and opportunity, while safeguarding the integrity of Earth\'s life-supporting systems. The conceptual framework of s
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Despite the challenges since the Safe Motherhood Initiative
2019-06-01
Despite the challenges, since the Safe Motherhood Initiative was launched almost 30 years ago, international institutions such as the World Bank and WHO, and independent groups such as the Institute for Health Metrics and Evaluation, have developed, published, and continually refined estimates of ma
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br As outlined in in
2019-06-01
As outlined in in October, 2016, my vision for WHO can be summed up in five words: equity, rights, responsiveness, evidence, and partnership. In this ci-1033 context, I am pleased to respond to the authors of the open letter in , on the leadership role that WHO must play in tackling the high pri
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In high income settings the prevalence of tobacco use has
2019-06-01
In high-income settings, the prevalence of tobacco use has been shown to be significantly higher in people living with HIV than among HIV-negative individuals of the same age and sex distribution. This at-risk pattern is one of the biggest threats to the number of years of life saved with antiretrov
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Worldwide there are an estimated
2019-05-31
Worldwide, there are an estimated 1 112 727 specialist surgeons (IQR 1 059 158–1 177 912), 550 134 anaesthesiologists (529 008–572 916) and 483 357 obstetricians (456 093–517 638; ). Low-income and lower-middle-income countries, representing 48% of the global population, have 20% of this workforce,
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Funding US Centers for Disease Control and Prevention
2019-05-31
Funding US Centers for Disease Control and Prevention, US President\'s Malaria Initiative, Doris Duke Charitable Foundation, and Alpha Omega Alpha Honor Society. Declaration of interests Abstract Background Injuries are the cause of almost 6 million deaths every year, with 15–20% of these assoc
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br Discussion Prehabilitation is a program to enhance
2019-05-31
Discussion “Prehabilitation” is a program to enhance functional capacity and psychological health to enable patients to withstand an upcoming stressor, e.g. surgery. It is intended to reduce treatment-related morbidity and/or mortality, to decrease length of hospital stay and/or re-admission, and
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br Material and methods br
2019-05-31
Material and methods Results Discussion Conclusions Conflict of interest Acknowledgments Introduction Matching the morphology of paced complexes to tachycardia complexes is useful for mapping arrhythmias. In the atrium, pace mapping is useful for focal atrial arrhythmias in orde
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br With respect to the welfare of
2019-05-30
With respect to the welfare of children and mothers, the transition from the Millennium Development Goals (MDGs) to Sustainable Development Goals (SDGs) is sometimes perceived as risky. The relevant MDGs had a focus on interventions to address maternal and child health, while the focus of the SDGs
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br Materials and methods br Results br Discussion
2019-05-30
Materials and methods Results Discussion The treatment regimen used in this study is generally safe and well tolerated. The process of generating therapeutic numbers of CART-138 Cy3-dUTP by limiting their dilutions proved to be quite difficult; however, the target cell dose was reached with
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Patients with syncope often suffer secondary trauma Major mo
2019-05-30
Patients with syncope often suffer secondary trauma. Major morbidities such as fractures and injuries from motor vehicle accidents have been reported in 6% of patients, whereas minor injuries such as lacerations and bruises have been reported in 29% [1]. Recurrent syncope was associated with fractur
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Introduction Cardiac resynchronization therapy CRT reduces m
2019-05-30
Introduction Cardiac resynchronization therapy (CRT) reduces mortality and morbidity in selected heart failure patients with impaired left ventricular (LV) function and cardiac dyssynchrony [1]. Most patients receive CRT with a defibrillator (CRT-D) because the indications for an implantable cardio
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More recently Brugada et al used flecainide to identify
2019-05-30
More recently, Brugada et al. [131]. used flecainide to identify the full extent of low-voltage electrogram activity in the anterior RV and RVOT and targeted this region for RFA. In all 14 BrS patients, RFA eliminated abnormal bipolar electrograms, normalized ST-segment elevation on right precordial
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